5-hydroxy-L-tryptophan + H₂O → 5-hydroxyindole + ammonium + pyruvate (R00830)
- Silencing
  - Genome
H₂O + 7,8-dihydroneopterin 3'-triphosphate → H⁺ + acetaldehyde + 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate (R1962)
- Silencing
  - Genome
    - Escherichia coli NMS-19
    - Escherichia coli NMS-20
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + oxygen → 5-hydroxy-L-tryptophan + (6R)-4a-hydroxy-tetrahydrobiopterin (R10224)
- Overexpression
  - Plasmid
    - Escherichia coli NMS-19
    - Escherichia coli NMS-20
NADP⁺ + 5,6,7,8-tetrahydromonapterin ← 7,8-dihydromonapterin + NADPH + H⁺ (R3129)
- Overexpression
  - Plasmid
    - Escherichia coli NMS-19
    - Escherichia coli NMS-20
7,8-dihydroneopterin 3'-triphosphate ↔ 7,8-dihydromonapterin triphosphate (R3127)
- Overexpression
  - Plasmid
    - Escherichia coli NMS-19
    - Escherichia coli NMS-20
L-dopa + H⁺ → dopamine + CO₂ (R2733)
- Overexpression
  - Plasmid
S-ribosyl-L-homocysteine + adenine ↔ H₂O + S-adenosyl-L-homocysteine (R211)
- Overexpression
  - Plasmid
S-ribosyl-L-homocysteine → L-homocysteine + autoinducer 2 (R585)
- Overexpression
  - Plasmid
H₂O + L-methionine + ATP → S-adenosyl-L-methionine + diphosphate + phosphate (R279)
- Overexpression
  - Plasmid
serotonin + (R)-S-adenosyl-L-methionine → N-Methylserotonin + H⁺ + S-adenosyl-L-homocysteine (R00791)
- Overexpression
  - Plasmid
    - Escherichia coli NMS-11
    - Escherichia coli NMS-4