D-threo-isocitrate ↔ glyoxylate + succinate (R1019)
- Silencing
  - Genome
coenzyme A + succinate + ATP ↔ succinyl-CoA + phosphate + ADP (R1049)
- Silencing
  - Genome
pyruvate + ATP ↔ phosphoenolpyruvate + H⁺ + ADP (R345)
- Silencing
  - Genome
pyruvate + GTP ← phosphoenolpyruvate + H⁺ + GDP (R1153)
- Silencing
  - Genome
H⁺ + phosphoenolpyruvate + UDP → pyruvate + UTP (R00861)
- Silencing
  - Genome
phosphoenolpyruvate + CDP + H⁺ → pyruvate + CTP (R00862)
- Silencing
  - Genome
phosphoenolpyruvate + dTDP + H⁺ → pyruvate + dTTP (R00863)
- Silencing
  - Genome
acetyl-CoA + phosphate ↔ coenzyme A + acetyl phosphate (R424)
- Silencing
  - Genome
    - Escherichia coli ita19
    - Escherichia coli ita23
NADP⁺ + D-threo-isocitrate → NADPH + 2-oxoglutarate + CO₂ (R384)
- Attenuation
  - Genome
    - Escherichia coli ita23
cis-aconitate → itaconate + CO₂ (R5005)
- Overexpression
  - Plasmid
H₂O + acetyl-CoA + oxaloacetate → coenzyme A + H⁺ + citrate (R92)
- Overexpression
  - Plasmid