• D-erythrose 4-phosphate + phosphoenolpyruvate + H₂O ↔ 3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (R576)
  • Feedback insensitive
    • Plasmid
      • Escherichia coli BTY0.5
      • Escherichia coli BTY1.5
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli BTY0.10
      • Escherichia coli BTY1.10
      • Escherichia coli BTY0.11
      • Escherichia coli BTY1.11
      • Escherichia coli BTY0.12
      • Escherichia coli BTY1.12
      • Escherichia coli BTY0.13
      • Escherichia coli BTY1.13
      • Escherichia coli BTY2.13
      • Escherichia coli HGA6
      • Escherichia coli HGC4
      • Escherichia coli BTY5.13
      • Escherichia coli HGB6
      • Escherichia coli BTY7.13
      • Escherichia coli HGD
      • Escherichia coli HGC1
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli HGC2
      • Escherichia coli WSH-Z06 (pAP12)
      • Escherichia coli WSH-Z06 (pAP11)
      • Escherichia coli WSH-Z06 (pAP01)
      • Escherichia coli WSH-Z06 (pAP01) ΔldhA
      • Escherichia coli WSH-Z06 (pAP01) ΔpflB
      • Escherichia coli WSH-Z06 (pAP01) ΔadhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtrpE
      • Escherichia coli WSH-Z06 (pAP01) ΔpheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,ldhA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,ldhA
      • Escherichia coli HGD1
      • Escherichia coli HGD3
      • Escherichia coli W3110_TIR
      • Escherichia coli W3110ΔtyrR_TIR
      • Escherichia coli T1
      • Escherichia coli T2
      • Escherichia coli VH33_TIR
      • Escherichia coli VH33ΔtyrR_TIR
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
      • Escherichia coli HGD2
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^fbr tyrA^WT)
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^fbr tyrA^fbr)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1aroG^fbr tyrA^fbr ppsA)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1 aroG^fbr tyrA^fbr tktA)
      • Escherichia coli HGC3
      • Escherichia coli BTY1.1
      • Escherichia coli BTY1.2
    • Genome
      • Escherichia coli DPD4193
  • Overexpression
    • Plasmid
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^WT tyrA^WT)
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^WT tyrA^fbr)
  • Silencing
    • Genome
      • Escherichia coli DPD4193
• prephenate + NAD⁺ → NADH + 3-(4-hydroxyphenyl)pyruvate + CO₂ (R727)
  • Feedback insensitive
    • Plasmid
      • Escherichia coli BTY0.5
      • Escherichia coli BTY1.5
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli BTY0.10
      • Escherichia coli BTY1.10
      • Escherichia coli BTY0.11
      • Escherichia coli BTY1.11
      • Escherichia coli BTY0.12
      • Escherichia coli BTY1.12
      • Escherichia coli BTY0.13
      • Escherichia coli BTY1.13
      • Escherichia coli BTY2.13
      • Escherichia coli HGA6
      • Escherichia coli HGC4
      • Escherichia coli BTY5.13
      • Escherichia coli HGB6
      • Escherichia coli BTY7.13
      • Escherichia coli HGD
      • Escherichia coli HGC1
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli HGC2
      • Escherichia coli WSH-Z06 (pAP12)
      • Escherichia coli WSH-Z06 (pAP11)
      • Escherichia coli WSH-Z06 (pAP01)
      • Escherichia coli WSH-Z06 (pAP01) ΔldhA
      • Escherichia coli WSH-Z06 (pAP01) ΔpflB
      • Escherichia coli WSH-Z06 (pAP01) ΔadhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtrpE
      • Escherichia coli WSH-Z06 (pAP01) ΔpheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,ldhA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,ldhA
      • Escherichia coli HGD1
      • Escherichia coli HGD3
      • Escherichia coli T1
      • Escherichia coli T2
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
      • Escherichia coli HGD2
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^WT tyrA^fbr)
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^fbr tyrA^fbr)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1aroG^fbr tyrA^fbr ppsA)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1 aroG^fbr tyrA^fbr tktA)
      • Escherichia coli HGC3
      • Escherichia coli BTY0.3
      • Escherichia coli BTY0.4
  • Overexpression
    • Plasmid
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^WT tyrA^WT)
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^fbr tyrA^WT)
      • Escherichia coli W3110_TIR
      • Escherichia coli VH33_TIR
      • Escherichia coli W3110ΔtyrR_TIR
      • Escherichia coli VH33ΔtyrR_TIR
    • Genome
      • Escherichia coli DPD4193
• chorismate ↔ prephenate (R69)
  • Feedback insensitive
    • Plasmid
      • Escherichia coli BTY0.5
      • Escherichia coli BTY1.5
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli BTY0.10
      • Escherichia coli BTY1.10
      • Escherichia coli BTY0.11
      • Escherichia coli BTY1.11
      • Escherichia coli BTY0.12
      • Escherichia coli BTY1.12
      • Escherichia coli BTY0.13
      • Escherichia coli BTY1.13
      • Escherichia coli BTY2.13
      • Escherichia coli HGA6
      • Escherichia coli HGC4
      • Escherichia coli BTY5.13
      • Escherichia coli HGB6
      • Escherichia coli BTY7.13
      • Escherichia coli HGD
      • Escherichia coli HGC1
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli HGC2
      • Escherichia coli WSH-Z06 (pAP12)
      • Escherichia coli WSH-Z06 (pAP11)
      • Escherichia coli WSH-Z06 (pAP01)
      • Escherichia coli WSH-Z06 (pAP01) ΔldhA
      • Escherichia coli WSH-Z06 (pAP01) ΔpflB
      • Escherichia coli WSH-Z06 (pAP01) ΔadhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtrpE
      • Escherichia coli WSH-Z06 (pAP01) ΔpheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,ldhA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,ldhA
      • Escherichia coli HGD1
      • Escherichia coli HGD3
      • Escherichia coli T1
      • Escherichia coli T2
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
      • Escherichia coli HGD2
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^WT tyrA^fbr)
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^fbr tyrA^fbr)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1aroG^fbr tyrA^fbr ppsA)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1 aroG^fbr tyrA^fbr tktA)
      • Escherichia coli HGC3
      • Escherichia coli BTY0.3
      • Escherichia coli BTY0.4
  • Overexpression
    • Plasmid
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^WT tyrA^WT)
      • Escherichia coli K12 ΔtyrR (pCL1920::aroG^fbr tyrA^WT)
      • Escherichia coli W3110_TIR
      • Escherichia coli VH33_TIR
      • Escherichia coli W3110ΔtyrR_TIR
      • Escherichia coli VH33ΔtyrR_TIR
    • Genome
      • Escherichia coli DPD4193
• H₂O + pyruvate + ATP ↔ H⁺ + phosphoenolpyruvate + phosphate + AMP (R346)
  • Overexpression
    • Plasmid
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1aroG^fbr tyrA^fbr ppsA)
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGB6
      • Escherichia coli HGC1
      • Escherichia coli T2
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
      • Escherichia coli WSH-Z06 (pAP11)
    • Genome
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• D-erythrose 4-phosphate + D-xylulose 5-phosphate ↔ β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate (R372)
  • Overexpression
    • Plasmid
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGB6
      • Escherichia coli HGC1
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli WSH-Z06 (pAP11)
      • Escherichia coli W3110_TIR
      • Escherichia coli VH33_TIR
      • Escherichia coli W3110ΔtyrR_TIR
      • Escherichia coli VH33ΔtyrR_TIR
      • Escherichia coli T2
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1 aroG^fbr tyrA^fbr tktA)
    • Genome
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ↔ aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate (R584)
  • Overexpression
    • Plasmid
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGB6
      • Escherichia coli HGC1
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli WSH-Z06 (pAP11)
      • Escherichia coli W3110_TIR
      • Escherichia coli VH33_TIR
      • Escherichia coli W3110ΔtyrR_TIR
      • Escherichia coli VH33ΔtyrR_TIR
      • Escherichia coli T2
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
      • Escherichia coli K12 ΔtyrR (pCL1920::P_LtetO−1 aroG^fbr tyrA^fbr tktA)
    • Genome
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• shikimate + ATP ↔ shikimate 3-phosphate + H⁺ + ADP (R400)
  • Overexpression
    • Plasmid
      • Escherichia coli BTY0.10
      • Escherichia coli BTY1.10
      • Escherichia coli BTY0.11
      • Escherichia coli BTY1.11
      • Escherichia coli BTY0.12
      • Escherichia coli BTY1.12
      • Escherichia coli BTY0.13
      • Escherichia coli BTY1.13
      • Escherichia coli BTY2.13
      • Escherichia coli BTY5.13
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli BTY7.13
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• L-tyrosine + H⁺ ↔ L-tyrosine + H⁺ (R00807)
  • Silencing
    • Genome
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGB6
      • Escherichia coli HGC1
      • Escherichia coli BTY2.13
      • Escherichia coli HGC2
      • Escherichia coli HGC4
      • Escherichia coli BTY5.13
      • Escherichia coli HGC3
      • Escherichia coli BTY7.13
      • Escherichia coli HGD
• prephenate + H⁺ ↔ H₂O + 3-phenyl-2-oxopropanoate + CO₂ (R511)
  • Silencing
    • Genome
      • Escherichia coli HGA1
      • Escherichia coli HGA2
      • Escherichia coli HGA3
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli HGA6
      • Escherichia coli HGB6
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
      • Escherichia coli WSH-Z06 (pAP01) ΔpheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,trpE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,pflB
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,ldhA
      • Escherichia coli DPD4193
• shikimate + NADP⁺ ↔ 3-dehydroshikimate + NADPH + H⁺ (R607)
  • Overexpression
    • Plasmid
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• 3-dehydroquinate ↔ H₂O + 3-dehydroshikimate (R538)
  • Overexpression
    • Plasmid
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• 3-deoxy-D-arabino-heptulosonate 7-phosphate → 3-dehydroquinate + phosphate (R68)
  • Overexpression
    • Plasmid
      • Escherichia coli WSH-Z06 (pAP12)
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli HGA6
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• 2-oxoglutarate + L-tyrosine ↔ 3-(4-hydroxyphenyl)pyruvate + L-glutamate (R428)
  • Overexpression
    • Plasmid
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• 5-enolpyruvoyl-shikimate 3-phosphate → phosphate + chorismate (R339)
  • Overexpression
    • Plasmid
      • Escherichia coli WSH-Z06 (pAP12)
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli HGA6
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• phosphoenolpyruvate + shikimate 3-phosphate ↔ 5-enolpyruvoyl-shikimate 3-phosphate + phosphate (R126)
  • Overexpression
    • Plasmid
      • Escherichia coli WSH-Z06 (pAP12)
      • Escherichia coli HGA4
      • Escherichia coli HGA5
      • Escherichia coli HGA6
      • Escherichia coli A (pS0, pY0)
      • Escherichia coli WSH-Z06 (pAP21)
      • Escherichia coli C (pS4, pY1)
      • Escherichia coli D (pS5, pY1)
      • Escherichia coli E (pS4, pY2)
      • Escherichia coli F (pS4, pY3)
      • Escherichia coli G (pS5, pY3)
• L-glutamine + chorismate ↔ anthranilate + pyruvate + H⁺ + L-glutamate (R10)
  • Silencing
    • Genome
      • Escherichia coli WSH-Z06 (pAP01) ΔtrpE
      • Escherichia coli HGA1
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,trpE
      • Escherichia coli HGA4
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,trpE
      • Escherichia coli HGB6
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• L-alanine ↔ D-alanine (R733)
  • Silencing
    • Genome
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• L-tyrosine → L-tyrosine (R00806)
  • Overexpression
    • Genome
      • Escherichia coli HGC1
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
    • Plasmid
      • Escherichia coli HGB6
• NADH + NADP⁺ + H⁺ → NADPH + NAD⁺ + H⁺ (R427)
  • Overexpression
    • Genome
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• β-D-fructofuranose 6-phosphate + phosphate → D-erythrose 4-phosphate + acetyl phosphate + H₂O (R2193)
  • Overexpression
    • Plasmid
      • Escherichia coli HGC2
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD2
      • Escherichia coli HGD3
      • Escherichia coli HGD
• acetyl-CoA + phosphate ↔ coenzyme A + acetyl phosphate (R424)
  • Overexpression
    • Plasmid
      • Escherichia coli HGC3
      • Escherichia coli HGC4
      • Escherichia coli HGD1
      • Escherichia coli HGD3
      • Escherichia coli HGD
  • Silencing
    • Genome
      • Escherichia coli HGD2
• H₂O + pyruvate + ubiquinone-8 → acetate + ubiquinol-8 + CO₂ (R4535)
  • Silencing
    • Genome
      • Escherichia coli HGD3
      • Escherichia coli HGD
• NAD⁺ + (R)-lactate ← NADH + pyruvate + H⁺ (R504)
  • Silencing
    • Genome
      • Escherichia coli WSH-Z06 (pAP01) ΔldhA
      • Escherichia coli HGA3
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,ldhA
      • Escherichia coli HGA6
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,pheA,ldhA
• formate + acetyl-CoA ↔ coenzyme A + pyruvate (R278)
  • Silencing
    • Genome
      • Escherichia coli WSH-Z06 (pAP01) ΔpflB
• ethanol + NAD⁺ ↔ acetaldehyde + NADH + H⁺ (R157)
  • Silencing
    • Genome
      • Escherichia coli HGA2
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔadhE
      • Escherichia coli HGA5
• coenzyme A + acetaldehyde + NAD⁺ ↔ NADH + H⁺ + acetyl-CoA (R156)
  • Silencing
    • Genome
      • Escherichia coli HGA2
      • Escherichia coli WSH-Z06 (pAP01) ΔtyrR,adhE
      • Escherichia coli WSH-Z06 (pAP01) ΔadhE
      • Escherichia coli HGA5
• acetate + ATP ↔ acetyl phosphate + ADP (R45)
  • Silencing
    • Genome
      • Escherichia coli HGD1
• phosphoenolpyruvate + β-D-glucopyranose → β-D-glucose 6-phosphate + pyruvate (R4216)
  • Silencing
    • Genome
      • Escherichia coli VH33_TIR
      • Escherichia coli VH33ΔtyrR_TIR
• D-Glucose + H⁺ → D-Glucose + H⁺ (R00800)
  • Overexpression
    • Genome
      • Escherichia coli VH33_TIR
      • Escherichia coli VH33ΔtyrR_TIR