acetyl-CoA ↔ coenzyme A + acetoacetyl-CoA (R12)
- Overexpression
  - Plasmid
NADP⁺ + coenzyme A + (R)-mevalonate ↔ NADPH + H⁺ + (S)-3-hydroxy-3-methylglutaryl-CoA (R668)
- Overexpression
  - Plasmid
H₂O + acetoacetyl-CoA + acetyl-CoA ↔ coenzyme A + H⁺ + (S)-3-hydroxy-3-methylglutaryl-CoA (R685)
- Overexpression
  - Plasmid
(R)-mevalonate + ATP ↔ (R)-5-phosphomevalonate + H⁺ + ADP (R630)
- Overexpression
  - Plasmid
(R)-5-phosphomevalonate + ATP ↔ (R)-mevalonate diphosphate + ADP (R716)
- Overexpression
  - Plasmid
(R)-mevalonate diphosphate + ATP → isopentenyl diphosphate + phosphate + ADP + CO₂ (R465)
- Overexpression
  - Plasmid
isopentenyl diphosphate ↔ prenyl diphosphate (R123)
- Overexpression
  - Plasmid
neryl diphosphate → nerol + diphosphate (R00797)
- Overexpression
  - Plasmid
    - Escherichia coli ENO2
    - Escherichia coli ENO1
isopentenyl diphosphate + prenyl diphosphate → diphosphate + neryl diphosphate (R9293)
- Overexpression
  - Plasmid