Compound as reactive (2)

trans-4-hydroxy-L-proline → H₂O + H⁺ + (S)-1-pyrroline-5-carboxylate

2 trans-4-hydroxy-L-proline + oxygen → 2 H₂O + 2 (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + 2 H⁺

Compound as product (2)

trans-4-hydroxy-L-proline + NAD(P)+ ← 2 H⁺ + (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + NAD(P)H

2-oxoglutarate + L-proline + oxygen → trans-4-hydroxy-L-proline + succinate + CO₂

Reversible reaction (2)

trans-4-hydroxy-L-proline + NAD⁺ ↔ 2 H⁺ + 4-oxoproline + NADH

trans-4-hydroxy-L-proline ↔ cis-4-hydroxy-D-proline