Compound as reactive (3)

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol + (S)-2-hydroxyglutarate → demethylated 7,8-dihydromethanopterin + diphosphate

oxygen + (S)-2-hydroxyglutarate → hydrogen peroxide + 2-oxoglutarate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol + (S)-2-hydroxyglutarate → 7,8-dihydromethanopterin + diphosphate

Compound as product (1)

glutarate + 2-oxoglutarate + oxygen → (S)-2-hydroxyglutarate + CO₂ + succinate

Reversible reaction (2)

NAD⁺ + (S)-2-hydroxyglutarate ↔ NADH + 2-oxoglutarate + H⁺

an oxidized electron donor + (S)-2-hydroxyglutarate ↔ a reduced electron donor + 2-oxoglutarate