Titer in Flask for L-dopa

Strain Production
mg/L
100
200
300
400
500
600
700
E. coli BW25113 (pQE-hpaBC)
E. coli AROM-1 (pQE-hpaBC)
E. coli AROM-3 (pQE-hpaBC)
E. coli AROM-2 (pQE-hpaBC)
E. coli AROM-4 (pQE-hpaBC)
E. coli TYR-1 (pQE-hpaBC)
E. coli DOPA-30 (pQE30)
E. coli W3110ΔtyrR_DOPA
E. coli DOPA-1
E. coli VH33ΔtyrR_DOPA
E. coli DOPA-30 (pQE30-2hpaBC)
E. coli DOPA-30N
E. coli DOPA-30 (pQE30-phaBCN)

Titer in Fed-Batch for L-dopa

Strain Production
mg/L
1000
2000
3000
4000
5000
6000
7000
8000
9000
E. coli DOPA-30N

Titer in Batch for L-dopa

Strain Production
mg/L
400.0
800.0
1200.0
1600.0
2000.0
E. coli VH33ΔtyrR_DOPA

Volumetric productivity in Fed-Batch for L-dopa

Strain Production
mg/L/h
30.0
60.0
90.0
120.0
150.0
E. coli DOPA-30N

Substrate yield in Fed-Batch for L-dopa

Strain Production
g/g of sustrate
0.01
0.02
0.03
0.04
0.05
0.06
0.07
E. coli DOPA-30N

Substrate yield in Flask for L-dopa

Strain Production
g/g of sustrate
0.01
0.02
0.03
0.04
0.05
0.06
E. coli W3110ΔtyrR_DOPA
E. coli VH33ΔtyrR_DOPA