Escherichia coli A (pS0, pY0)

Ancestors
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | Plasmid pS0 added | Plasmid pY0 added

Bars (|) indicate differences between strains.


Plasmids
  • pS0 (pSC101 ori, PLtetO-1-ydiB-aroD-aroB-aroG*-ppsA-tktA)

    pY0 (p15A ori, Plac-UV5-tyrB-tyrA*-aroC-aroA-aroK)


Modifications
Origin Gene Organism Modification
pS0
Overexpression
pS0
Overexpression
pS0
Overexpression
pS0
Feedback insensitive
pS0
Overexpression
pS0
Overexpression
pY0
Overexpression
pY0
Feedback insensitive
pY0
Overexpression
pY0
Overexpression
pY0
Overexpression

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-tyrosine Titer 746.0 mg/L 24 h Flask [244]
L-tyrosine Biomass-specific yield 921.0 mg/g DCW 24 h Flask [244]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References