Escherichia coli Y6-7

Ancestors
Genotype with respect to parental

ynci:: PBBa_j 23110-thrA


Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ∆xdhABC | ∆purR | ygay:: Ptrc-purFBsD293V.K316Q.S400W | yeep::Ptrc- prsEcD128A | ilvg::Ptrc- purFDNTSQLMKECBBs | ycgh:: Ptrc- addEc, yjiT::Ptrc-adeEc | ylbe::Ptrc-isn1Sc | ∆hpt | ∆guaB | rph::PapFAB104-EsaR | yghe::PesaS-guaB | ycdn:: PBBa_j 23110esaI | yjip::Ptrc-pur(FDNTSQLMKECB) | yeel::Ptrc- glnABsL159I, E304A | yjgx::Plac-aspC | ynci:: PBBa_j 23110-thrA

Bars (|) indicate differences between strains.


Modifications
Origin Gene Organism Modification
Silencing
Silencing
Silencing
Silencing
Feedback insensitive
Feedback insensitive
Silencing
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
add
Overexpression
Overexpression
Overexpression
hpt
Silencing
Silencing
rph
Silencing
Overexpression
Attenuation
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Feedback insensitive
Overexpression
Attenuation

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
hypoxanthine Titer 3.94 g/L * 47.0 OD600* Flask [256]
hypoxanthine Substrate yield 0.067 g/g of sustrate * 47.0 OD600* Flask [256]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References