Escherichia coli Dmtr-Y
Ancestors
Genotype with respect to parental
Δmtr
Genotype with respect to wild type
F+ (λ) | ΔtrpR Δtna | Plasmid pSV-709 added | Plasmid pMEL03 added | Δmtr | Plasmid pMEL03 lost | Plasmid pMEL03-Y addedBars (|) indicate differences between strains.
Plasmids
Modifications
| Origin | Gene | Organism | Modification |
|---|---|---|---|
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Silencing
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Silencing
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Silencing
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Silencing
|
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Overexpression
|
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Overexpression
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Overexpression
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Overexpression
|
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Overexpression
|
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Feedback insensitive
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Feedback insensitive
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Overexpression
|
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Overexpression
|
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tryptophan | Substrate yield | 19.45 % | Fed-Batch | [133] | |||
| L-tryptophan | Titer | 46.27 g/L * | 36 h * | Fed-Batch | [133] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.