Escherichia coli VAL15

Strain derived from a randomly mutated strain.

Ancestors

Derived strains

Genotype with respect to parental

brnQ::brnFE


Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔlacI | PilvC::Ptrc | PilvDE::Ptrc | △brnQ | brnQ::brnFE

Bars (|) indicate differences between strains.


Modifications
Origin Gene Organism Modification
Silencing
Overexpression
Overexpression
Overexpression
Silencing
Overexpression
Overexpression

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-valine Titer 70.0 g/L Fed-Batch [321]
L-valine Substrate yield 0.26 g/g of sustrate Fed-Batch [321]
L-valine Volumetric productivity 1.46 g/L/h Fed-Batch [321]
L-valine Titer 55.0 g/L Fed-Batch [321]
L-valine Titer 14.1 g/L Flask [321]
L-valine Substrate yield 0.22 g/g of sustrate Flask [321]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References