Escherichia coli DA-25
Ancestors
Derived strains
Genotype with respect to parental
gapC::Ptrc-hpaBC, rph::PT7-DmDdc
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | lacI::PxylA-T7 RNA Polymerase, △tynA | ylbE::Ptrc-hpaBC, yjiK::PT7-DmDdc | △tyrR, ygaY::Ptrc-aroGfbr, ycgH::Ptrc-tyrAfbr | yciQ::Ptrc-aroE, yeeL::Ptrc-tyrB | △pykF | yncK::Ptrc-pps | yeeP::Ptrc-tktA, yjgX::Ptrc-talB | yghE::Ptrc-hpaBC, mbhA::PT7-DmDdc | gapC::Ptrc-hpaBC, rph::PT7-DmDdcBars (|) indicate differences between strains.
Modifications
| Origin | Gene | Organism | Modification |
|---|---|---|---|
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Silencing
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Silencing
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Silencing
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Overexpression
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Overexpression
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Silencing
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Overexpression
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Silencing
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Silencing
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Feedback insensitive
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Silencing
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Feedback insensitive
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Silencing
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Overexpression
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Silencing
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Overexpression
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Silencing
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Silencing
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Overexpression
|
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Silencing
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Overexpression
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Silencing
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Overexpression
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Silencing
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Overexpression
|
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Overexpression
|
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|
Silencing
|
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Overexpression
|
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Silencing
|
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Overexpression
|
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Overexpression
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Silencing
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| dopamine | Titer | 4.58 g/L | Flask | [323] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.