Escherichia coli HIS2-1
This strain does not exhibit an improved production of the intended metabolite when compared with its closest ancestors.
Ancestors
Genotype with respect to parental
ΔhisJ
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔlacI, ylbE::Ptrc-CghisGfbr | hisLG::Ptrc | ilvG::Ptrc-CghisGfbr | ycgH::Ptrc-CghisGfbr | ygaY::Ptrc-CghisGfbr | tfaD::Ptrc-CghisGfbr | ycdN::Ptrc-CghisGfbr | ΔhisJBars (|) indicate differences between strains.
Modifications
| Origin | Gene | Organism | Modification |
|---|---|---|---|
|
Silencing
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Silencing
|
|||
|
Silencing
|
|||
|
Overexpression
|
|||
|
Overexpression
|
|||
|
Overexpression
|
|||
|
Overexpression
|
|||
|
Overexpression
|
|||
|
Overexpression
|
|||
|
Overexpression
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Silencing
|
|||
|
Feedback insensitive
|
|||
|
Silencing
|