Escherichia coli TC36
Ancestors
Derived strains
Genotype with respect to parental
W3110, (Succ+), ΔfocA-pflB::FRT ΔfrdBC ΔldhA Δatp(FH)::FRT ΔadhE::FRT ΔsucA::FRT
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | W3110, (Succ+), ΔfocA-pflB::FRT ΔfrdBC ΔldhA Δatp(FH)::FRT ΔadhE::FRT ΔsucA::FRTBars (|) indicate differences between strains.
Modifications
| Origin | Gene | Organism | Modification |
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Silencing
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Silencing
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| pyruvate | Titer | 81.0 mM | 16 h | Fed-Batch | [185] | ||
| pyruvate | Titer | 38.1 mM | 3.47 g/L | 20 h | Batch | [185] | |
| acetate | Titer | 197.7 mM | 3.47 g/L | 20 h | Batch | [185] | |
| 2-oxoglutarate | Titer | 16.6 mM | 3.47 g/L | 20 h | Batch | [185] | |
| succinate | Titer | 13.7 mM | 3.47 g/L | 20 h | Batch | [185] | |
| fumarate | Titer | 1.4 mM | 3.47 g/L | 20 h | Batch | [185] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.