Escherichia coli TYR-1 (pQE-hpaBC)
Ancestors
Genotype with respect to wild type
F+ (λ) | IacIq rrnBT14 ∆lacZWJ16 hsdR514 ∆araBADAH33 ∆rhaBADLD78 | ΔtyrR, ΔcsrA | ΔptsHI, Δcrr | P37-galP-P37-glk | Δzwf | ΔpheLA | Plasmid pQE30-hpaBC addedBars (|) indicate differences between strains.
Plasmids
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pQE30-hpaBC (PT5-hpaBC)
Modifications
| Origin | Gene | Organism | Modification |
|---|---|---|---|
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Silencing
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Silencing
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Silencing
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Silencing
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Silencing
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Overexpression
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Overexpression
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Silencing
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Silencing
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Silencing
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Overexpression
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-dopa | Titer | 209.2 mg/L | 4.59 OD600 | Flask | [342] | ||
| L-tyrosine | Titer | 256.6 mg/L | 4.59 OD600 | Flask | [342] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.