Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications
Titer in Flask for psilocybin
| Modifications | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain | Maximum production | tnaAEc | Arg5Av | DDCCK | psiMPc | psiKPc | psiMPc | trpEEc | trpDEc | trpCEc | trpBEc | trpAEc | aroLEc | ppsAEc | tktAEc | aroGEc |
| E. coli PP08 | 393.22 mg/L | |||||||||||||||
| E. coli PP26 | 423.56 mg/L | |||||||||||||||
| E. coli PP27 | 557.91 mg/L | |||||||||||||||
| E. coli PP07 | 562.9 mg/L | |||||||||||||||
| E. coli PP11 | 639 mg/L | |||||||||||||||
| E. coli PP09 | 700 mg/L | |||||||||||||||
| E. coli PP10 | 776.36 mg/L | |||||||||||||||
Titer in Fed-Batch for psilocybin
| Modifications | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain | Maximum production | tnaAEc | Arg5Av | DDCCK | psiMPc | psiKPc | trpEEc | trpDEc | trpCEc | trpBEc | trpAEc | aroLEc | ppsAEc | tktAEc | aroGEc |
| E. coli PP27 | 2,000 mg/L | ||||||||||||||
Volumetric productivity in Fed-Batch for psilocybin
| Modifications | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain | Maximum production | tnaAEc | Arg5Av | DDCCK | psiMPc | psiKPc | trpEEc | trpDEc | trpCEc | trpBEc | trpAEc | aroLEc | ppsAEc | tktAEc | aroGEc |
| E. coli PP27 | 26.7 mg/L/h | ||||||||||||||